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CDAI-PRO2 Calculator

Two items from the CDAI that you report yourself, stools and tummy pain over a week, used in many trials of new Crohn’s medicines.

CDAI-PRO2 uses two of the CDAI’s diary items, the number of liquid or very soft stools and how bad tummy pain was, averaged over 7 days. Medicines regulators want trials to measure what patients report, so it was developed in 2015 from the CDAI and is now used in many trials of new Crohn’s medicines.

It needs no blood test, weight or examination, only a daily note for a week. The original study linked its scores to CDAI scores: a PRO2 of 8 corresponds to a CDAI of 150, 14 to 220 and 34 to 450. Your IBD team may use the full CDAI or another score instead.

Work out your CDAI-PRO2 score

Liquid or very soft stools (poos)

The number each day, for the last 7 days.

Points: the daily average × 2.

Abdominal (tummy) pain

How bad it was each day, for the last 7 days.

  • 0 None
  • 1 Mild
  • 2 Moderate
  • 3 Severe

Points: the daily average × 5.

How the CDAI-PRO2 score is used where you live

Australia

CDAI-PRO2 was developed for clinical trials of new Crohn’s medicines, and is used mainly in them. Ask your IBD team whether they use it.

Canada

CDAI-PRO2 was developed for clinical trials of new Crohn’s medicines, and is used mainly in them. Ask your IBD team whether they use it.

New Zealand

CDAI-PRO2 was developed for clinical trials of new Crohn’s medicines, and is used mainly in them. Ask your IBD team whether they use it.

United Kingdom

CDAI-PRO2 was developed for clinical trials of new Crohn’s medicines, and is used mainly in them. Ask your IBD team whether they use it.

United States

CDAI-PRO2 was developed for clinical trials of new Crohn’s medicines, and is used mainly in them. Ask your IBD team whether they use it.

Somewhere else

CDAI-PRO2 was developed for clinical trials of new Crohn’s medicines, and is used mainly in them. Ask your IBD team whether they use it.

What the total means

The CDAI-PRO2 score describes how active Crohn’s disease looks from the answers given. It doesn’t diagnose anything, and your IBD team reads it alongside everything else they know about you.

  • Under 8: corresponds to a CDAI under 150, the range trials use for remission
  • 8 to under 14: corresponds to a CDAI of 150 to 219, the range later studies call mild
  • 14 to 34: corresponds to a CDAI of 220 to 450, the range later studies call moderate
  • Over 34: corresponds to a CDAI over 450, the range the original CDAI study linked with extremely severe disease

Sources